Drug-Gene Testing

Drug-gene testing is also known as pharmacogenetics or pharmacogenomics. All terms characterize the analysis of how your genes affect the human body’s response to drugs. The term “pharmacogenomic” is combined from the terms pharmacology (the study of the effects and uses of medications) and genomics (the analysis of genes and their functions).

Your body has thousands of genes which you inherited from your parents. Genes define which features you have, such as blood type and eye color. Some genes are liable for how your body processes medications. Pharmacogenomic tests examine for modifications or variations in these genes that may ascertain if a medication could be a useful treatment for you or if you might have side effects to a particular medication.

Pharmacogenomic testing is one means that can help your health care provider decide the best medicine for you. Your health care provider also examines other factors like your age, lifestyle, other medications you are taking, and your general health when choosing the ideal treatment for you.

Pharmacogenomics Program Animation

The Pharmacogenomics Program examines how mutations in genes influence response to medications, thereby using a patient’s genetic profile to estimate a drug’s efficacy, guide dosage, and promote patient safety.

What is the purpose of Pharmacogenomics Testing?

The purpose of pharmacogenomic testing is to determine if a medication is ideal for you. A little blood or saliva sample can help determine:

  • If medication may be an effective treatment for you
  • What the best dose of a drug is for you
  • Whether you could have severe side effects from a medication

The lab looks for changes or variants in one or more genes that could influence your reaction to certain medicines.

Every person would need to have the same specific Pharmacogenomics test just once because your genetic makeup doesn’t change over time. However, you might require different pharmacogenomics tests if you choose another medication. Each medication is related to different pharmacogenomics test. Keep a record of your test results and share them with your medical care providers.

The requirement for pharmacogenomics testing depends on an individual basis. If your pharmacogenomics test results imply you might not have a fantastic reaction to a medicine, your relatives may have a similar response. We advise you to discuss this information with your relatives. Your healthcare provider can also offer recommendations for family members who might benefit from having testing.

Genomic Sequencing Cartoon

Genomic sequencing is a procedure for assessing a sample of DNA obtained from your blood. In the laboratory, technicians obtain DNA and make it ready for sequencing.

Admera Health also provides DNA testing that a physician can order for their patients to find out which medication will work best for them.

DNA testing blood sample for Pharmacogenomics

Frequently Asked Questions

What is Pharmacogenomics?

Pharmacogenomics is the study of genetic variants that affect an individual’s response to medications. Pharmacogenomics is a combination of genomics and pharmacology. Pharmacology is the part of science which studies how drugs work. Genomics is the study of an individual’s genome, such as the interactions of these genes with each other and with the individual’s environment. Each individual responds uniquely to treatment, while one treatment approach may work well for a single person; the same method might not be effective or may cause adverse drug effects in different patients. The execution of pharmacogenomics may help doctors make informed treatment choices. This may result in better results by decreasing adverse drug events and by increasing the potency of drugs.

What is PGx Testing?

Pharmacogenomics (PGx) or pharmacogenetics is a tool utilized to provide insight into how a patient may respond to certain medications

How it Works

  1. Provide a buccal swab, mouth wash, blood, or saliva sample
  2. Ship the specimen to Admera Health
  3. Admera Health scientists sequence and interpret DNA
  4. Receive a personalized genetic report

credit:  Admera Health

Who Should Ask For Pharmacogenomics Testing?

Pharmacogenomics testing is advised for any patient who is taking drugs where the FDA approves or requires PGx testing.

Pharmacogenomics testing is also suggested for polypharmacy patients and any individual who is receiving drug treatment.

Why Pick PGxOne™ Pharmacogenomics Testing?

PGxOne™ Plus gives complete coverage. It measures 53 genes in one test covering 200 variants. PGxOne™ Plus uses the most superior technology NGS, presents clinically technical and clinically relevant data. NGS presents comprehensive genetic variant coverage and effective at discovering Copy Number Variations, insertions, deletions, and substitutions. It applies proprietary bioinformatics methods for data analysis and interpretation. The procedure is simple and convenient and has a quick turn-around-time.

Which Are Specimen Submission Requirements PGxOne™ One?

Particular submission specifications are as follows: PGxOne™ Plus testing utilizes DNA isolated from buccal swabs, mouthwash/oral rinse, saliva, or blood.

Mouthwash/Oral Rinse:  Measuring cup, scope mouthwash, and collection tube are supplied to the Physician. Fill the measuring cup near the top with mouthwash. Swish deeply for a minimum 15 seconds then spot all the mouthwash from your mouth into the collection tube. Repeat twice to be sure the collection tube is filled at least to the 40ml lines.

Blood: DNA blood tube is offered to the Physician. Take at least 2mls of blood in lavender top vacutainer, which comprises EDTA as an anticoagulant. Quickly invert the tube 8 to 10 times to assure anticoagulation and mixing of the samples.

Buccal Swabs: Two swabs are given in the test supplies given to the doctor by Admera Health. The two swabs can be used to acquire buccal cells in the patient’s cheeks as per the instructions provided. The swabs should be put into the collection tube as directed.

Saliva: One saliva collection supply is given to the physician. The tube must contain saliva to the black wavy line as detailed in the instructions provided. After collection, tighten the cap and shake the tube for at least five seconds to ensure proper mixing of the spit with the stabilizing solutions.

How Are Strong Profiling and Liquid Biopsy Different Than Other Cancer Testing Procedures?

Oncology tumor profiling tests sequence numerous genes or particular spots on genes at the same time to discover the existence of known cancer-causing variations, such as single nucleotide variations, insertions and deletions, copy number variations, and fusions. Most other testing modalities aren’t comprehensive, examining for just one protein or gene, and are unable to detect the existence of numerous mutation types.

OncoGxOne™ is Admera’s most comprehensive clinical enzyme providing Next Generation Sequencing panel available, such as 56 genes link to cancer.

OncoGxSelect™ is a smaller Next Generation Sequencing panel that’s intend to align with nationally recognized cancer guidelines.

LiguidGx™ can be used to identify cancer-driving variations but from a blood sample. Two testing modes are available, a Next-Generation Sequencing panel and an establish qPCR method according to preference/need.


What Can Be Learn From Solid Tumor Profiling and Liquid Biopsy Tests?

Admera’s tumor profiling tests can identify the existence of known mutations for patients who were diagnosed with cancer, especially solid tumors. With this knowledge, Admera provides recommendations on which target treatments are most likely to be beneficial and which ones aren’t. Relevant clinical trial data based on geography will also be provided (five clinical trials/mutation found). Sometimes, along with target treatment recommendations, prognosis information associated with the mutation/s detected can be obtained.

What Are Specimen Submission Specifications For Admera’s Cancer Tests?

For solid tumor profiling from tissue ( OncoGxSelect™ & OncoGxOne™), the preferred sample type is Formalin-Fixed, Paraffin-Embedded (FFPE) Slides, including Fine-Needle Aspirates and Core Needle Biopsies. The optimal tissue includes >= 1 mm3 tissue e.g., >= 25 mm2 surfaces place x 40 µm depths on 8 to 10 unstained slides. For smaller/impure samples, extra unstained slides may be required. If the patient treated with target treatment, the post-therapy sample submits when available.

What’s ctDNA and Why Is It Important?

Fragments of DNA, known as cell-free DNA (cfDNA), flow smoothly in the blood. Circulating tumor DNA or CtDNA  is a kind of cfDNA that’s been shed of off tumors to the bloodstream. CtDNA can be used to determine known mutations associated with some types of cancer. LiquidGx™ also finds ctRNA for fusion detection.

When Is Testing with Admera’s Health Cardiovascular Test Portfolio Advice?

Genetic testing can help in the differential diagnosis, risk assessment, and guide treatment choices for patients with cardiovascular diseases and ailments. Patients are great candidates for genetic testing if they have a close family relative who has had cardiovascular disease. Familial testing is suggested for the screening of first-degree family members of people who were diagnosed with a disease-causing mutation or where sudden cardiac death has occurred.


Which are Specimen Submission Prerequisites For Admera’s Inherit Cardiovascular Tests?

Saliva: One saliva collection device and related return packaging give to the physician. The tube must contain saliva to the line as detailed in the provided instructions. After collection, remove the cap from the dropper bottle, and empty the contents into the saliva collection device. Unscrew the funnel in the sample tube and discard. Take care not to spill any of the liquid. Screw the tube cap on the sample tube until it’s tightly sealed and mix smoothly by inverting the sample tube multiple times.

Blood: A lavender top vacutainer tube comprising ETDA is use to collect up to 5 ml of blood. After the set, invert the sample tube 8 to 10 times to ensure proper mixing. Please, note, blood samples should be sent with the enclosed cold pack.

How Does It Take To Get The Evaluation Results?

PGxOne™ Plus test results will be available within 7-10 business days after receipt of the sample in our laboratory.

LiquidGx™ test results will normally be available within three days for qPCR evaluations and 3-5 for NGS tests.

OncoGxSelect™ And OncoGxOne™ test results will typically be available within 7-10 business days after receipt of the sample in our laboratory.

AtheroGxOne™ And CarioGxOne™ test results will typically be available in 3-4 weeks after receipt of the individual samples.

Does Insurance cover Admera Test Tests?

To verify coverage by your insurance provider, please call Admera Health Billing.  Phone: 1-908-222-0533; press option 2

How Much Can Admera Health Cost?

Please make a call at 1-908-222-0533, option 2 for any billing queries

How To Order More Supplies?

If you want more test supplies, contact: Admera Health Client Care

Phone: 1-908-222-0533, press option 1


Alternatively, Admera Health has partnered with a logistics firm that monitors supply volume through barcode scanning and will automatically renew inventory once 70% of the supplies have been utilized.

What Do I Contact To Get More Information?

Admera Health Client Care


Phone: 1-908-222-0533; press option 1

General Inquiries Email:


Leave a Reply

Your email address will not be published.

This site uses Akismet to reduce spam. Learn how your comment data is processed.